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Role of synovial fibroblast subsets across synovial pathotypes in rheumatoid arthritis: a deconvolution analysis

OBJECTIVES: To integrate published single-cell RNA sequencing (scRNA-seq) data and assess the contribution of synovial fibroblast (SF) subsets to synovial pathotypes and respective clinical characteristics in treatment-naïve early arthritis. METHODS: In this in silico study, we integrated scRNA-seq...

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Detalles Bibliográficos
Autores principales: Micheroli, Raphael, Elhai, Muriel, Edalat, Sam, Frank-Bertoncelj, Mojca, Bürki, Kristina, Ciurea, Adrian, MacDonald, Lucy, Kurowska-Stolarska, Mariola, Lewis, Myles J, Goldmann, Katriona, Cubuk, Cankut, Kuret, Tadeja, Distler, Oliver, Pitzalis, Costantino, Ospelt, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734041/
https://www.ncbi.nlm.nih.gov/pubmed/34987094
http://dx.doi.org/10.1136/rmdopen-2021-001949