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AHSA1 is a promising therapeutic target for cellular proliferation and proteasome inhibitor resistance in multiple myeloma

BACKGROUND: Currently, multiple myeloma (MM) is still an incurable plasma cell malignancy in urgent need of novel therapeutic targets and drugs. METHODS: Bufalin was known as a highly toxic but effective anti-cancer compound. We used Bufalin as a probe to screen its potential targets by proteome mic...

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Detalles Bibliográficos
Autores principales: Gu, Chunyan, Wang, Yajun, Zhang, Lulin, Qiao, Li, Sun, Shanliang, Shao, Miaomiao, Tang, Xiaozhu, Ding, Pinggang, Tang, Chao, Cao, Yuhao, Zhou, Yanyan, Guo, Mengjie, Wei, Rongfang, Li, Nianguang, Xiao, Yibei, Duan, Jinao, Yang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734095/
https://www.ncbi.nlm.nih.gov/pubmed/34991674
http://dx.doi.org/10.1186/s13046-021-02220-1