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Computational Study of Mechanism and Enantioselectivity of Imine Reductase from Amycolatopsis orientalis

Imine reductases (IREDs) are NADPH‐dependent enzymes (NADPH=nicotinamide adenine dinucleotide phosphate) that catalyze the reduction of imines to amines. They exhibit high enantioselectivity for a broad range of substrates, making them of interest for biocatalytic applications. In this work, we have...

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Detalles Bibliográficos
Autores principales: Prejanò, Mario, Sheng, Xiang, Himo, Fahmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734122/
https://www.ncbi.nlm.nih.gov/pubmed/34825518
http://dx.doi.org/10.1002/open.202100250