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Computational Study of Mechanism and Enantioselectivity of Imine Reductase from Amycolatopsis orientalis
Imine reductases (IREDs) are NADPH‐dependent enzymes (NADPH=nicotinamide adenine dinucleotide phosphate) that catalyze the reduction of imines to amines. They exhibit high enantioselectivity for a broad range of substrates, making them of interest for biocatalytic applications. In this work, we have...
Autores principales: | Prejanò, Mario, Sheng, Xiang, Himo, Fahmi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734122/ https://www.ncbi.nlm.nih.gov/pubmed/34825518 http://dx.doi.org/10.1002/open.202100250 |
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