The CD70-CD27 axis in oncology: the new kids on the block

The immune checkpoint molecule CD70 and its receptor CD27 are aberrantly expressed in many hematological and solid malignancies. Dysregulation of the CD70-CD27 axis within the tumor and its microenvironment is associated with tumor progression and immunosuppression. This is in contrast to physiologi...

Descripción completa

Detalles Bibliográficos
Autores principales: Flieswasser, Tal, Van den Eynde, Astrid, Van Audenaerde, Jonas, De Waele, Jorrit, Lardon, Filip, Riether, Carsten, de Haard, Hans, Smits, Evelien, Pauwels, Patrick, Jacobs, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734249/
https://www.ncbi.nlm.nih.gov/pubmed/34991665
http://dx.doi.org/10.1186/s13046-021-02215-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734249/
https://www.ncbi.nlm.nih.gov/pubmed/34991665
http://dx.doi.org/10.1186/s13046-021-02215-y

Ejemplares similares