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Evaluation of CRISPR gene-editing tools in zebrafish

BACKGROUND: Zebrafish have practical features that make them a useful model for higher-throughput tests of gene function using CRISPR/Cas9 editing to create ‘knockout’ models. In particular, the use of G(0) mosaic mutants has potential to increase throughput of functional studies significantly but m...

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Detalles Bibliográficos
Autores principales: Uribe-Salazar, José M., Kaya, Gulhan, Sekar, Aadithya, Weyenberg, KaeChandra, Ingamells, Cole, Dennis, Megan Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734261/
https://www.ncbi.nlm.nih.gov/pubmed/34986794
http://dx.doi.org/10.1186/s12864-021-08238-1