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Evaluation of CRISPR gene-editing tools in zebrafish
BACKGROUND: Zebrafish have practical features that make them a useful model for higher-throughput tests of gene function using CRISPR/Cas9 editing to create ‘knockout’ models. In particular, the use of G(0) mosaic mutants has potential to increase throughput of functional studies significantly but m...
Autores principales: | Uribe-Salazar, José M., Kaya, Gulhan, Sekar, Aadithya, Weyenberg, KaeChandra, Ingamells, Cole, Dennis, Megan Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734261/ https://www.ncbi.nlm.nih.gov/pubmed/34986794 http://dx.doi.org/10.1186/s12864-021-08238-1 |
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