More than just a ticket canceller: the mitochondrial processing peptidase tailors complex precursor proteins at internal cleavage sites

Most mitochondrial proteins are synthesized as precursors that carry N-terminal presequences. After they are imported into mitochondria, these targeting signals are cleaved off by the mitochondrial processing peptidase (MPP). Using the mitochondrial tandem protein Arg5,6 as a model substrate, we dem...

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Detalles Bibliográficos
Autores principales: Friedl, Jana, Knopp, Michael R., Groh, Carina, Paz, Eyal, Gould, Sven B., Herrmann, Johannes M., Boos, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734313/
https://www.ncbi.nlm.nih.gov/pubmed/32997570
http://dx.doi.org/10.1091/mbc.E20-08-0524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734313/
https://www.ncbi.nlm.nih.gov/pubmed/32997570
http://dx.doi.org/10.1091/mbc.E20-08-0524

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