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More than just a ticket canceller: the mitochondrial processing peptidase tailors complex precursor proteins at internal cleavage sites
Most mitochondrial proteins are synthesized as precursors that carry N-terminal presequences. After they are imported into mitochondria, these targeting signals are cleaved off by the mitochondrial processing peptidase (MPP). Using the mitochondrial tandem protein Arg5,6 as a model substrate, we dem...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734313/ https://www.ncbi.nlm.nih.gov/pubmed/32997570 http://dx.doi.org/10.1091/mbc.E20-08-0524 |