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Mitochondrial Dynamics Mediated by DRP1 and MFN2 Contributes to Cisplatin Chemoresistance in Human Ovarian Cancer SKOV3 cells

Cisplatin (DDP) is the first-line chemotherapeutic agent for ovarian cancer. However, the development of DDP resistance seriously influences the chemotherapeutic effect and prognosis of ovarian cancer. It was reported that DDP can directly impinge on the mitochondria and activate the intrinsic apopt...

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Detalles Bibliográficos
Autores principales: Zou, Guang-Ping, Yu, Chun-Xia, Shi, Sheng-Lan, Li, Qiu-Gen, Wang, Xiao-Hua, Qu, Xin-Hui, Yang, Zhang-Jian, Yao, Wei-Rong, Yan, Dan-Dan, Jiang, Li-Ping, Wan, Yu-Ying, Han, Xiao-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734405/
https://www.ncbi.nlm.nih.gov/pubmed/35003356
http://dx.doi.org/10.7150/jca.61379