In search of autophagy biomarkers in breast cancer: Receptor status and drug agnostic transcriptional changes during autophagy flux in cell lines

Autophagy drives drug resistance and drug-induced cancer cell cytotoxicity. Targeting the autophagy process could greatly improve chemotherapy outcomes. The discovery of specific inhibitors or activators has been hindered by challenges with reliably measuring autophagy levels in a clinical setting....

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Detalles Bibliográficos
Autores principales: Mascia, Francesca, Mazo, Ilya, Alterovitz, Wei-Lun, Karagiannis, Konstantinos, Wu, Wells W., Shen, Rong-Fong, Beaver, Julia A., Rao, V. Ashutosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735604/
https://www.ncbi.nlm.nih.gov/pubmed/34990474
http://dx.doi.org/10.1371/journal.pone.0262134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735604/
https://www.ncbi.nlm.nih.gov/pubmed/34990474
http://dx.doi.org/10.1371/journal.pone.0262134

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