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In search of autophagy biomarkers in breast cancer: Receptor status and drug agnostic transcriptional changes during autophagy flux in cell lines
Autophagy drives drug resistance and drug-induced cancer cell cytotoxicity. Targeting the autophagy process could greatly improve chemotherapy outcomes. The discovery of specific inhibitors or activators has been hindered by challenges with reliably measuring autophagy levels in a clinical setting....
Autores principales: | Mascia, Francesca, Mazo, Ilya, Alterovitz, Wei-Lun, Karagiannis, Konstantinos, Wu, Wells W., Shen, Rong-Fong, Beaver, Julia A., Rao, V. Ashutosh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735604/ https://www.ncbi.nlm.nih.gov/pubmed/34990474 http://dx.doi.org/10.1371/journal.pone.0262134 |
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