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Long range PCR-based deep sequencing for haplotype determination in mixed HCMV infections

BACKGROUND: Short read sequencing has been used extensively to decipher the genome diversity of human cytomegalovirus (HCMV) strains, but falls short to reveal individual genomes in mixed HCMV strain populations. Novel third-generation sequencing platforms offer an extended read length and promise t...

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Detalles Bibliográficos
Autores principales: Brait, Nadja, Külekçi, Büşra, Goerzer, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735729/
https://www.ncbi.nlm.nih.gov/pubmed/34991471
http://dx.doi.org/10.1186/s12864-021-08272-z