S-540956, a CpG Oligonucleotide Annealed to a Complementary Strand With an Amphiphilic Chain Unit, Acts as a Potent Cancer Vaccine Adjuvant by Targeting Draining Lymph Nodes

Robust induction of cancer-antigen-specific CD8(+) T cells is essential for the success of cancer peptide vaccines, which are composed of a peptide derived from a cancer-specific antigen and an immune-potentiating adjuvant, such as a Toll-like receptor (TLR) agonist. Efficient delivery of a vaccine...

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Detalles Bibliográficos
Autores principales: Nakagawa, Takayuki, Tanino, Tetsuya, Onishi, Motoyasu, Tofukuji, Soichi, Kanazawa, Takayuki, Ishioka, Yukichi, Itoh, Takeshi, Kugimiya, Akira, Katayama, Kazufumi, Yamamoto, Takuya, Nagira, Morio, Ishii, Ken J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735836/
https://www.ncbi.nlm.nih.gov/pubmed/35003132
http://dx.doi.org/10.3389/fimmu.2021.803090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735836/
https://www.ncbi.nlm.nih.gov/pubmed/35003132
http://dx.doi.org/10.3389/fimmu.2021.803090

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