Targeting MyD88 Downregulates Inflammatory Mediators and Pathogenic Processes in PBMC From DMARDs-Naïve Rheumatoid Arthritis Patients

MyD88-dependent intracellular signalling cascades and subsequently NF-kappaB-mediated transcription lead to the dynamic inflammatory processes underlying the pathogenesis of rheumatoid arthritis (RA) and related autoimmune diseases. This study aimed to identify the effect of the MyD88 dimerization i...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramirez-Perez, Sergio, Oregon-Romero, Edith, Reyes-Perez, Itzel Viridiana, Bhattaram, Pallavi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735861/
https://www.ncbi.nlm.nih.gov/pubmed/35002734
http://dx.doi.org/10.3389/fphar.2021.800220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735861/
https://www.ncbi.nlm.nih.gov/pubmed/35002734
http://dx.doi.org/10.3389/fphar.2021.800220

Ejemplares similares