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Cell membrane-anchored anti-HIV single-chain antibodies and bifunctional inhibitors targeting the gp41 fusion protein: new strategies for HIV gene therapy

Emerging studies indicate that infusion of HIV-resistant cells could be an effective strategy to achieve a sterilizing or functional cure. We recently reported that glycosylphosphatidylinositol (GPI)-anchored nanobody or a fusion inhibitory peptide can render modified cells resistant to HIV-1 infect...

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Detalles Bibliográficos
Autores principales: Chen, Yue, Jin, Hongliang, Tang, Xiaoran, Li, Li, Geng, Xiuzhu, Zhu, Yuanmei, Chong, Huihui, He, Yuxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735881/
https://www.ncbi.nlm.nih.gov/pubmed/34821542
http://dx.doi.org/10.1080/22221751.2021.2011616