Induction of serine hydroxymethyltransferase 2 promotes tumorigenesis and metastasis in neuroblastoma

High-risk neuroblastoma (NB) remains an extremely difficult subgroup to cure and is associated with MYCN amplification. Serine hydroxymethyltransferase 2 (SHMT2) regulates serine metabolism in a myc-dependent manner; it is upregulated in several cancers and is associated with tumor aggressiveness. A...

Descripción completa

Detalles Bibliográficos
Autores principales: Clark, Rachael A., Qiao, Jingbo, Jacobson, Jillian C., Chung, Dai H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735882/
https://www.ncbi.nlm.nih.gov/pubmed/35018218
http://dx.doi.org/10.18632/oncotarget.28168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735882/
https://www.ncbi.nlm.nih.gov/pubmed/35018218
http://dx.doi.org/10.18632/oncotarget.28168

Ejemplares similares