Mechanism of life-long maintenance of neuron identity despite molecular fluctuations

Cell fate is maintained over long timescales, yet molecular fluctuations can lead to spontaneous loss of this differentiated state. Our simulations identified a possible mechanism that explains life-long maintenance of ASE neuron fate in Caenorhabditis elegans by the terminal selector transcription...

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Detalles Bibliográficos
Autores principales: Traets, Joleen JH, van der Burght, Servaas N, Rademakers, Suzanne, Jansen, Gert, van Zon, Jeroen S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735970/
https://www.ncbi.nlm.nih.gov/pubmed/34908528
http://dx.doi.org/10.7554/eLife.66955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735970/
https://www.ncbi.nlm.nih.gov/pubmed/34908528
http://dx.doi.org/10.7554/eLife.66955

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