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Mechanism of life-long maintenance of neuron identity despite molecular fluctuations
Cell fate is maintained over long timescales, yet molecular fluctuations can lead to spontaneous loss of this differentiated state. Our simulations identified a possible mechanism that explains life-long maintenance of ASE neuron fate in Caenorhabditis elegans by the terminal selector transcription...
Autores principales: | Traets, Joleen JH, van der Burght, Servaas N, Rademakers, Suzanne, Jansen, Gert, van Zon, Jeroen S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735970/ https://www.ncbi.nlm.nih.gov/pubmed/34908528 http://dx.doi.org/10.7554/eLife.66955 |
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