Cargando…

High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism

The molecular motor myosin undergoes a series of major structural transitions during its force-producing motor cycle. The underlying mechanism and its coupling to ATP hydrolysis and actin binding are only partially understood, mostly due to sparse structural data on actin-bound states of myosin. Her...

Descripción completa

Detalles Bibliográficos
Autores principales: Pospich, Sabrina, Sweeney, H Lee, Houdusse, Anne, Raunser, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735999/
https://www.ncbi.nlm.nih.gov/pubmed/34812732
http://dx.doi.org/10.7554/eLife.73724