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Activated Factor XI is Increased in Plasma in Response to Surgical Trauma but not to Recombinant Activated FVII-Induced Thrombin Formation

Aim: Feedback activation of factor XI (FXI) by thrombin is believed to play a critical role in the amplification phase of thrombin generation and to contribute to thrombosis development and hemostasis. However, the activation of FXI by thrombin has been shown in vitro to require a cofactor. In this...

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Detalles Bibliográficos
Autores principales: Rühl, Heiko, Friemann, Anne M., Reda, Sara, Schwarz, Nadine, Winterhagen, Franziska I., Berens, Christina, Müller, Jens, Oldenburg, Johannes, Pötzsch, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8737067/
https://www.ncbi.nlm.nih.gov/pubmed/33298665
http://dx.doi.org/10.5551/jat.59873