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Activated Factor XI is Increased in Plasma in Response to Surgical Trauma but not to Recombinant Activated FVII-Induced Thrombin Formation
Aim: Feedback activation of factor XI (FXI) by thrombin is believed to play a critical role in the amplification phase of thrombin generation and to contribute to thrombosis development and hemostasis. However, the activation of FXI by thrombin has been shown in vitro to require a cofactor. In this...
Autores principales: | Rühl, Heiko, Friemann, Anne M., Reda, Sara, Schwarz, Nadine, Winterhagen, Franziska I., Berens, Christina, Müller, Jens, Oldenburg, Johannes, Pötzsch, Bernd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japan Atherosclerosis Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8737067/ https://www.ncbi.nlm.nih.gov/pubmed/33298665 http://dx.doi.org/10.5551/jat.59873 |
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