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Nanoparticle-Mediated Delivery of Pitavastatin to Monocytes/Macrophages Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apoe (−/−) Mice

Aim: Abdominal aortic aneurysm (AAA) is a lethal and multifactorial disease. To prevent a rupture and dissection of enlarged AAA, prophylactic surgery and stenting are currently available. There are, however, no medical therapies preventing these complications of AAA. Statin is one of the candidates...

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Detalles Bibliográficos
Autores principales: Katsuki, Shunsuke, Koga, Jun-ichiro, Matoba, Tetsuya, Umezu, Ryuta, Nakashiro, Soichi, Nakano, Kaku, Tsutsui, Hiroyuki, Egashira, Kensuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8737070/
https://www.ncbi.nlm.nih.gov/pubmed/33455994
http://dx.doi.org/10.5551/jat.54379