Iron-doxorubicin prodrug loaded liposome nanogenerator programs multimodal ferroptosis for efficient cancer therapy

Ferroptosis is a new mode of cell death, which can be induced by Fenton reaction-mediated lipid peroxidation. However, the insufficient H(2)O(2) and high GSH in tumor cells restrict the efficiency of Fenton reaction-dependent ferroptosis. Herein, a self-supplying lipid peroxide nanoreactor was devel...

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Detalles Bibliográficos
Autores principales: Yang, Yinxian, Zuo, Shiyi, Li, Linxiao, Kuang, Xiao, Li, Jinbo, Sun, Bingjun, Wang, Shujun, He, Zhonggui, Sun, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2021
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8737402/
https://www.ncbi.nlm.nih.gov/pubmed/35027953
http://dx.doi.org/10.1016/j.ajps.2021.05.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8737402/
https://www.ncbi.nlm.nih.gov/pubmed/35027953
http://dx.doi.org/10.1016/j.ajps.2021.05.001

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