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Iron-doxorubicin prodrug loaded liposome nanogenerator programs multimodal ferroptosis for efficient cancer therapy
Ferroptosis is a new mode of cell death, which can be induced by Fenton reaction-mediated lipid peroxidation. However, the insufficient H(2)O(2) and high GSH in tumor cells restrict the efficiency of Fenton reaction-dependent ferroptosis. Herein, a self-supplying lipid peroxide nanoreactor was devel...
Autores principales: | Yang, Yinxian, Zuo, Shiyi, Li, Linxiao, Kuang, Xiao, Li, Jinbo, Sun, Bingjun, Wang, Shujun, He, Zhonggui, Sun, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shenyang Pharmaceutical University
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8737402/ https://www.ncbi.nlm.nih.gov/pubmed/35027953 http://dx.doi.org/10.1016/j.ajps.2021.05.001 |
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