Regulation of Chemosensitivity in Human Medulloblastoma Cells by p53 and the PI3 Kinase Signaling Pathway

In medulloblastoma, p53 expression has been associated with chemoresistance and radiation resistance and with poor long-term outcomes in the p53-mutated sonic hedgehog, MYC-p53, and p53-positive medulloblastoma subgroups. We previously established a direct role for p53 in supporting drug resistance...

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Detalles Bibliográficos
Autores principales: Naeem, Aisha, Harish, Varsha, Coste, Sophie, Parasido, Erika M., Choudhry, Muhammad Umer, Kromer, Lawrence F., Ihemelandu, Chukuemeka, Petricoin, Emanuel F., Pierobon, Mariaelena, Noon, Muhammad Saad, Yenugonda, Venkata Mahidhar, Avantaggiati, Maria, Kupfer, Gary M., Fricke, Stanley, Rodriguez, Olga, Albanese, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Cancer “-Omics”
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738155/
https://www.ncbi.nlm.nih.gov/pubmed/34635507
http://dx.doi.org/10.1158/1541-7786.MCR-21-0277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738155/
https://www.ncbi.nlm.nih.gov/pubmed/34635507
http://dx.doi.org/10.1158/1541-7786.MCR-21-0277

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