Caspase-2 regulates S-phase cell cycle events to protect from DNA damage accumulation independent of apoptosis

In addition to its classical role in apoptosis, accumulating evidence suggests that caspase-2 has non-apoptotic functions, including regulation of cell division. Loss of caspase-2 is known to increase proliferation rates but how caspase-2 is regulating this process is currently unclear. We show that...

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Detalles Bibliográficos
Autores principales: Boice, Ashley G., Lopez, Karla E., Pandita, Raj K, Parsons, Melissa J, Charendoff, Chloe I, Charaka, Vijay, Carisey, Alexandre F., Pandita, Tej K., Bouchier-Hayes, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738157/
https://www.ncbi.nlm.nih.gov/pubmed/34718349
http://dx.doi.org/10.1038/s41388-021-02085-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738157/
https://www.ncbi.nlm.nih.gov/pubmed/34718349
http://dx.doi.org/10.1038/s41388-021-02085-w

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