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A systematic review of non-motor symptom evaluation in clinical trials for amyotrophic lateral sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is increasingly recognised as a multi-system disorder, presenting with common and impactful non-motor symptoms, such as neuropsychiatric symtpoms, cognitive and behavioural changes, pain, disordered sleep, fatigue and problematic saliva. AIM/HYPOTHESIS...

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Detalles Bibliográficos
Autores principales: Beswick, Emily, Forbes, Deborah, Hassan, Zack, Wong, Charis, Newton, Judith, Carson, Alan, Abrahams, Sharon, Chandran, Siddharthan, Pal, Suvankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738361/
https://www.ncbi.nlm.nih.gov/pubmed/34120226
http://dx.doi.org/10.1007/s00415-021-10651-1