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Synergy of epidermal growth factor (EGFR) and angiotensin II (AT1R) receptor determines composition and temporal pattern of transcriptome variation

The tyrosine kinase receptor EGFR and the G-protein-coupled receptor AT1R induce essential cellular responses, in part via receptor crosstalk with an unknown role in nuclear information transfer and transcription regulation. We investigated whether this crosstalk results in linear, EGFR-mediated nuc...

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Detalles Bibliográficos
Autores principales: Schreier, Barbara, Dubourg, Virginie, Hübschmann, Stefanie, Rabe, Sindy, Mildenberger, Sigrid, Gekle, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738452/
https://www.ncbi.nlm.nih.gov/pubmed/34921637
http://dx.doi.org/10.1007/s00018-021-04065-5