LKB1 deficiency upregulates RELM-α to drive airway goblet cell metaplasia

Targeting airway goblet cell metaplasia is a novel strategy that can potentially reduce the chronic obstructive pulmonary disease (COPD) symptoms. Tumor suppressor liver kinase B1 (LKB1) is an important regulator of the proliferation and differentiation of stem/progenitor cells. In this study, we re...

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Detalles Bibliográficos
Autores principales: Li, Yu, Zhang, Qiuyang, Li, Li, Hao, De, Cheng, Peiyong, Li, Kuan, Li, Xue, Wang, Jianhai, Wang, Qi, Du, Zhongchao, Ji, Hongbin, Chen, Huaiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738459/
https://www.ncbi.nlm.nih.gov/pubmed/34921639
http://dx.doi.org/10.1007/s00018-021-04044-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738459/
https://www.ncbi.nlm.nih.gov/pubmed/34921639
http://dx.doi.org/10.1007/s00018-021-04044-w

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