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Biased Survival Predictions When Appraising Health Technologies in Heterogeneous Populations

INTRODUCTION: Time-to-event data from clinical trials are routinely extrapolated using parametric models to estimate the cost effectiveness of novel therapies, but how this approach performs in the presence of heterogeneous populations remains unknown. METHODS: We performed a simulation study of sev...

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Detalles Bibliográficos
Autores principales: Gallacher, Daniel, Kimani, Peter, Stallard, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738626/
https://www.ncbi.nlm.nih.gov/pubmed/34580839
http://dx.doi.org/10.1007/s40273-021-01082-x