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Biased Survival Predictions When Appraising Health Technologies in Heterogeneous Populations
INTRODUCTION: Time-to-event data from clinical trials are routinely extrapolated using parametric models to estimate the cost effectiveness of novel therapies, but how this approach performs in the presence of heterogeneous populations remains unknown. METHODS: We performed a simulation study of sev...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738626/ https://www.ncbi.nlm.nih.gov/pubmed/34580839 http://dx.doi.org/10.1007/s40273-021-01082-x |