Targeting Cpt1a-Bcl-2 interaction modulates apoptosis resistance and fibrotic remodeling

The mitochondrial calcium uniporter (MCU) regulates metabolic reprogramming in lung macrophages and the progression of pulmonary fibrosis. Fibrosis progression is associated with apoptosis resistance in lung macrophages; however, the mechanism(s) by which apoptosis resistance occurs is poorly unders...

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Detalles Bibliográficos
Autores principales: Gu, Linlin, Surolia, Ranu, Larson-Casey, Jennifer L., He, Chao, Davis, Dana, Kang, Jungsoon, Antony, Veena B., Carter, A. Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738732/
https://www.ncbi.nlm.nih.gov/pubmed/34413485
http://dx.doi.org/10.1038/s41418-021-00840-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738732/
https://www.ncbi.nlm.nih.gov/pubmed/34413485
http://dx.doi.org/10.1038/s41418-021-00840-w

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