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De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer

Breast cancer heterogeneity has made it challenging to identify mechanisms critical to the initial stages of their genesis in vivo. Here, we sought to interrogate the role of YB-1 in newly arising human breast cancers as well as in established cell lines. In a first series of experiments, we found t...

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Detalles Bibliográficos
Autores principales: Lefort, Sylvain, El-Naggar, Amal, Tan, Susanna, Colborne, Shane, Negri, Gian Luca, Pellacani, Davide, Hirst, Martin, Gusterson, Barry, Morin, Gregg B., Sorensen, Poul H., Eaves, Connie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738742/
https://www.ncbi.nlm.nih.gov/pubmed/34294889
http://dx.doi.org/10.1038/s41418-021-00836-6