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A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival

The cell division cycle 25A (CDC25A) phosphatase is a key regulator of cell cycle progression that acts on the phosphorylation status of Cyclin–Cyclin-dependent kinase complexes, with an emergent role in the DNA damage response and cell survival control. The regulation of CDC25A activity and its pro...

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Detalles Bibliográficos
Autores principales: Lara-Chica, Maribel, Correa-Sáez, Alejandro, Jiménez-Izquierdo, Rafael, Garrido-Rodríguez, Martín, Ponce, Francisco J., Moreno, Rita, Morrison, Kimberley, Di Vona, Chiara, Arató, Krisztina, Jiménez-Jiménez, Carla, Morrugares, Rosario, Schmitz, M. Lienhard, de la Luna, Susana, de la Vega, Laureano, Calzado, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738746/
https://www.ncbi.nlm.nih.gov/pubmed/34363019
http://dx.doi.org/10.1038/s41418-021-00845-5