Cargando…
A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival
The cell division cycle 25A (CDC25A) phosphatase is a key regulator of cell cycle progression that acts on the phosphorylation status of Cyclin–Cyclin-dependent kinase complexes, with an emergent role in the DNA damage response and cell survival control. The regulation of CDC25A activity and its pro...
Autores principales: | Lara-Chica, Maribel, Correa-Sáez, Alejandro, Jiménez-Izquierdo, Rafael, Garrido-Rodríguez, Martín, Ponce, Francisco J., Moreno, Rita, Morrison, Kimberley, Di Vona, Chiara, Arató, Krisztina, Jiménez-Jiménez, Carla, Morrugares, Rosario, Schmitz, M. Lienhard, de la Luna, Susana, de la Vega, Laureano, Calzado, Marco A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738746/ https://www.ncbi.nlm.nih.gov/pubmed/34363019 http://dx.doi.org/10.1038/s41418-021-00845-5 |
Ejemplares similares
-
Updating dual-specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2): molecular basis, functions and role in diseases
por: Correa-Sáez, Alejandro, et al.
Publicado: (2020) -
Phosphorylation-dependent regulation of the NOTCH1 intracellular domain by dual-specificity tyrosine-regulated kinase 2
por: Morrugares, Rosario, et al.
Publicado: (2019) -
A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response
por: Roewenstrunk, Julia, et al.
Publicado: (2019) -
Emerging roles of DYRK2 in cancer
por: Tandon, Vasudha, et al.
Publicado: (2021) -
FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2
por: Jiménez-Izquierdo, Rafael, et al.
Publicado: (2023)