Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting

Mounting evidence indicates that immunogenic therapies engaging the unfolded protein response (UPR) following endoplasmic reticulum (ER) stress favor proficient cancer cell-immune interactions, by stimulating the release of immunomodulatory/proinflammatory factors by stressed or dying cancer cells....

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Detalles Bibliográficos
Autores principales: Rufo, Nicole, Korovesis, Dimitris, Van Eygen, Sofie, Derua, Rita, Garg, Abhishek D., Finotello, Francesca, Vara-Perez, Monica, Rožanc, Jan, Dewaele, Michael, de Witte, Peter A., Alexopoulos, Leonidas G., Janssens, Sophie, Sinkkonen, Lasse, Sauter, Thomas, Verhelst, Steven H. L., Agostinis, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738768/
https://www.ncbi.nlm.nih.gov/pubmed/34453119
http://dx.doi.org/10.1038/s41418-021-00853-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738768/
https://www.ncbi.nlm.nih.gov/pubmed/34453119
http://dx.doi.org/10.1038/s41418-021-00853-5

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