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Deletion of the nuclear localization sequence and C-terminus of parathyroid hormone–related protein decreases osteogenesis and chondrogenesis but increases adipogenesis and myogenesis in murine bone marrow stromal cells

The N-terminus of parathyroid hormone–related protein regulates bone marrow stromal cell differentiation. We hypothesized that the nuclear localization sequence and C-terminus are involved. MicroRNA and gene expression analyses were performed on bone marrow stromal cells from mice lacking the nuclea...

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Detalles Bibliográficos
Autores principales: Hildreth, Blake E, Hernon, Krista M, Dirksen, Wessel P, Leong, John, Supsavhad, Wachiraphan, Boyaka, Prosper N, Rosol, Thomas J, Toribio, Ramiro E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738845/
https://www.ncbi.nlm.nih.gov/pubmed/35003616
http://dx.doi.org/10.1177/2041731415609298