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Regucalcin ameliorates doxorubicin-induced cytotoxicity in Cos-7 kidney cells and translocates from the nucleus to the mitochondria

Doxorubicin (DOX) is a potent anticancer drug, which can have unwanted side-effects such as cardiac and kidney toxicity. A detailed investigation was undertaken of the acute cytotoxic mechanisms of DOX on kidney cells, using Cos-7 cells as kidney cell model. Cos-7 cells were exposed to DOX for a per...

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Detalles Bibliográficos
Autores principales: Mohammed, Noor A., Hakeem, Israa J., Hodges, Nikolas, Michelangeli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738856/
https://www.ncbi.nlm.nih.gov/pubmed/34904631
http://dx.doi.org/10.1042/BSR20211464