Cargando…
Regucalcin ameliorates doxorubicin-induced cytotoxicity in Cos-7 kidney cells and translocates from the nucleus to the mitochondria
Doxorubicin (DOX) is a potent anticancer drug, which can have unwanted side-effects such as cardiac and kidney toxicity. A detailed investigation was undertaken of the acute cytotoxic mechanisms of DOX on kidney cells, using Cos-7 cells as kidney cell model. Cos-7 cells were exposed to DOX for a per...
Autores principales: | Mohammed, Noor A., Hakeem, Israa J., Hodges, Nikolas, Michelangeli, Francesco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738856/ https://www.ncbi.nlm.nih.gov/pubmed/34904631 http://dx.doi.org/10.1042/BSR20211464 |
Ejemplares similares
-
Role of Mitochondria in Retinal Pigment Epithelial Aging and Degeneration
por: Tong, Yao, et al.
Publicado: (2022) -
Obesity and Fatty Acids Promote Mitochondrial Translocation of STAT3 Through ROS-Dependent Mechanisms
por: Conway, Rachel, et al.
Publicado: (2022) -
Mitochondria-associated membranes (MAMs): a potential therapeutic target for treating Alzheimer’s disease
por: Yu, Weiwei, et al.
Publicado: (2021) -
Metformin mitigates SASP secretion and LPS-triggered hyper-inflammation in Doxorubicin-induced senescent endothelial cells
por: Abdelgawad, Ibrahim Y., et al.
Publicado: (2023) -
Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma
por: Li, Xiaolong, et al.
Publicado: (2019)