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METTL14-mediated Lnc-LSG1 m6A modification inhibits clear cell renal cell carcinoma metastasis via regulating ESRP2 ubiquitination

Clear cell renal cell carcinoma (ccRCC) is the most lethal urological cancer and is characterized by a high rate of metastasis and relapse. N6-Methyladenosine (m(6)A) is implicated in various stages of cancer development. However, a thorough understanding of m(6)A-modified lncRNAs in ccRCC is lackin...

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Detalles Bibliográficos
Autores principales: Shen, Danyang, Ding, Lifeng, Lu, Zeyi, Wang, Ruyue, Yu, Chenhao, Wang, Huan, Zheng, Qiming, Wang, Xuliang, Xu, Wanjiang, Yu, Haifeng, Xu, Liwei, Wang, Mingchao, Yu, Shicheng, Zhu, Shibin, Qian, Jun, Xia, Liqun, Li, Gonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738955/
https://www.ncbi.nlm.nih.gov/pubmed/35036065
http://dx.doi.org/10.1016/j.omtn.2021.12.024