The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the Retina

Expansion of a CAG repeat in ATXN3 causes the dominant polyglutamine disease spinocerebellar ataxia type 3 (SCA3), yet the physiological role of ATXN3 remains unclear. Here, we focus on unveiling the function of Ataxin-3 (ATXN3) in the retina, a neurological organ amenable to morphological and physi...

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Detalles Bibliográficos
Autores principales: Toulis, Vasileios, García-Monclús, Sílvia, de la Peña-Ramírez, Carlos, Arenas-Galnares, Rodrigo, Abril, Josep F., Todi, Sokol V., Khan, Naheed, Garanto, Alejandro, do Carmo Costa, Maria, Marfany, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738964/
https://www.ncbi.nlm.nih.gov/pubmed/33176149
http://dx.doi.org/10.1016/j.celrep.2020.108360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738964/
https://www.ncbi.nlm.nih.gov/pubmed/33176149
http://dx.doi.org/10.1016/j.celrep.2020.108360

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