MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination

Global pandemics caused by influenza or coronaviruses cause severe disruptions to public health and lead to high morbidity and mortality. There remains a medical need for vaccines against these pathogens. CMV (cytomegalovirus) is a β-herpesvirus that induces uniquely robust immune responses in which...

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Detalles Bibliográficos
Autores principales: Kim, Yeonsu, Zheng, Xiaoyan, Eschke, Kathrin, Chaudhry, M. Zeeshan, Bertoglio, Federico, Tomić, Adriana, Krmpotić, Astrid, Hoffmann, Markus, Bar-On, Yotam, Boehme, Julia, Bruder, Dunja, Ebensen, Thomas, Brunotte, Linda, Ludwig, Stephan, Messerle, Martin, Guzman, Carlos, Mandelboim, Ofer, Hust, Michael, Pöhlmann, Stefan, Jonjić, Stipan, Čičin-Šain, Luka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739032/
https://www.ncbi.nlm.nih.gov/pubmed/34992275
http://dx.doi.org/10.1038/s41423-021-00814-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739032/
https://www.ncbi.nlm.nih.gov/pubmed/34992275
http://dx.doi.org/10.1038/s41423-021-00814-5

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