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Nobiletin Inhibits Non-Small-Cell Lung Cancer by Inactivating WNT/β-Catenin Signaling through Downregulating miR-15-5p

BACKGROUND: Nobiletin is a natural compound with anticancer activity; however, the mechanism is not clear. METHODS: The inhibitory effect of nobiletin on non-small-cell lung cancer (NSCLC) cells was examined using soft agar, Transwell, and apoptosis analyses. Cancer stemness was measured by sphere a...

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Detalles Bibliográficos
Autores principales: Han, Sang Hyup, Han, Jeong Hee, Chun, Wan Joo, Lee, Sang Soo, Kim, Hae Sung, Lee, Jin Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739175/
https://www.ncbi.nlm.nih.gov/pubmed/35003309
http://dx.doi.org/10.1155/2021/7782963