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Effect of Polymorphisms of ABCB1 and MTHFR on Methotrexate-Related Toxicities in Adults With Hematological Malignancies

Study of the association between single nucleotide polymorphisms (SNPs) of methotrexate (MTX) pathway genes and MTX-related toxicity in the treatment of hematological malignancies is popular. Here, we studied the association between SNPs of MTHFR and ABCB1 and MTX-related toxicity in 157 adult Chine...

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Detalles Bibliográficos
Autores principales: Han, Jian, Liu, Lu, Meng, Li, Guo, Huan, Zhang, Jin, Han, Zhi-Qiang, Hong, Zhen-Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739189/
https://www.ncbi.nlm.nih.gov/pubmed/35004279
http://dx.doi.org/10.3389/fonc.2021.759805