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The Role of T Lymphocytes in the Pathogenesis of Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hematopoietic stem cell genetic mutation disease that causes defective erythrocyte membrane hemolysis. Its pathologic basis is the mutation of the PIG-A gene, whose product is necessary for the synthesis of glycosylphosphatidylinositol (GPI) a...

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Detalles Bibliográficos
Autores principales: Li, Chenyuan, Dong, Xifeng, Wang, Huaquan, Shao, Zonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739213/
https://www.ncbi.nlm.nih.gov/pubmed/35003092
http://dx.doi.org/10.3389/fimmu.2021.777649