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Population pharmacokinetic and exposure–response analyses of elotuzumab plus pomalidomide and dexamethasone for relapsed and refractory multiple myeloma

PURPOSE: Elotuzumab plus pomalidomide/dexamethasone (E-Pd) demonstrated efficacy and safety in relapsed and refractory multiple myeloma (RRMM). The clinical pharmacology of elotuzumab [± lenalidomide/dexamethasone (Ld)] was characterized previously. These analyses describe elotuzumab population phar...

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Detalles Bibliográficos
Autores principales: Ide, Takafumi, Osawa, Mayu, Sanghavi, Kinjal, Vezina, Heather E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739320/
https://www.ncbi.nlm.nih.gov/pubmed/34825942
http://dx.doi.org/10.1007/s00280-021-04365-4