Sex-specific differences in direct osteoclastic versus indirect osteoblastic effects underlay the low bone mass of Pannexin1 deletion in TRAP-expressing cells in mice

Pannexin1 (Panx1) is a hemichannel-forming protein that participates in the communication of cells with the extracellular space. To characterize the role of osteoclastic Panx1 on bone, Panx1(fl/fl);TRAP-Cre (Panx1(ΔOc)) mice were generated, and compared to Panx1(fl/fl) littermates at 6 weeks of age....

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Detalles Bibliográficos
Autores principales: Deosthale, Padmini, Hong, Jung Min, Essex, Alyson L., Rodriguez, Wilyaret, Tariq, Dua, Sidhu, Harmandeep, Marcial, Alejandro, Bruzzaniti, Angela, Plotkin, Lilian I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739454/
https://www.ncbi.nlm.nih.gov/pubmed/35028339
http://dx.doi.org/10.1016/j.bonr.2021.101164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739454/
https://www.ncbi.nlm.nih.gov/pubmed/35028339
http://dx.doi.org/10.1016/j.bonr.2021.101164

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