Cargando…
Sex-specific differences in direct osteoclastic versus indirect osteoblastic effects underlay the low bone mass of Pannexin1 deletion in TRAP-expressing cells in mice
Pannexin1 (Panx1) is a hemichannel-forming protein that participates in the communication of cells with the extracellular space. To characterize the role of osteoclastic Panx1 on bone, Panx1(fl/fl);TRAP-Cre (Panx1(ΔOc)) mice were generated, and compared to Panx1(fl/fl) littermates at 6 weeks of age....
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739454/ https://www.ncbi.nlm.nih.gov/pubmed/35028339 http://dx.doi.org/10.1016/j.bonr.2021.101164 |