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Efficient In Vitro Generation of IL-22-Secreting ILC3 From CD34(+) Hematopoietic Progenitors in a Human Mesenchymal Stem Cell Niche

Innate lymphoid cells (ILCs) and in particular ILC3s have been described to be vital for mucosal barrier functions and homeostasis within the gastrointestinal (GI) tract. Importantly, IL-22-secreting ILC3 have been implicated in the control of inflammatory bowel disease (IBD) and were shown to reduc...

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Detalles Bibliográficos
Autores principales: Bennstein, Sabrina B., Weinhold, Sandra, Degistirici, Özer, Oostendorp, Robert A. J., Raba, Katharina, Kögler, Gesine, Meisel, Roland, Walter, Lutz, Uhrberg, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739490/
https://www.ncbi.nlm.nih.gov/pubmed/35003122
http://dx.doi.org/10.3389/fimmu.2021.797432