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Efficient In Vitro Generation of IL-22-Secreting ILC3 From CD34(+) Hematopoietic Progenitors in a Human Mesenchymal Stem Cell Niche
Innate lymphoid cells (ILCs) and in particular ILC3s have been described to be vital for mucosal barrier functions and homeostasis within the gastrointestinal (GI) tract. Importantly, IL-22-secreting ILC3 have been implicated in the control of inflammatory bowel disease (IBD) and were shown to reduc...
Autores principales: | Bennstein, Sabrina B., Weinhold, Sandra, Degistirici, Özer, Oostendorp, Robert A. J., Raba, Katharina, Kögler, Gesine, Meisel, Roland, Walter, Lutz, Uhrberg, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739490/ https://www.ncbi.nlm.nih.gov/pubmed/35003122 http://dx.doi.org/10.3389/fimmu.2021.797432 |
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